Consomic strain

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August undefined, 2024

http://www.informatics.jax.org/mgihome/nomen/strains.shtml WebJul 23, 2024 · The congenic strain R3 (C3H.NSY- [ D11Mit242-D11Mit168 ]) possessed the middle and distal region (segment C, D and E) of NSY-Chr 11 from the recombinant position between D11Mit274 and D11Mit242 to the telomere of Chr 11.

Systematic analysis of emotionality in consomic mouse strains ...

WebJun 29, 2016 · Background: Selecting chromosome substitution strains (CSSs, also called consomic strains/lines) used in the search for quantitative trait loci (QTLs) consistently … WebConsomic strains, also known as chromosome substitution strains, are powerful tools for assigning polygenes that control quantitative complex traits to specific … nec rl39 リモコン使えない

Genetic Dissection of Trabecular Bone Structure with Mouse ...

WebMar 3, 2010 · Chromosome 13 consomic and congenic rat strains were analyzed to investigate the pattern of genomic pathway utilization involved in protection against salt-sensitive hypertension and renal injury. Introgression of the entire Brown-Norway chromosome 13 (consomic SS-13(BN)) or nonoverlapping segments … WebB. Consomic Strains The process of generating congenic strains is very lengthy, because it takes many backcrosses to obtain an isogenic or homogeneous background. … WebB. Consomic Strains The process of generating congenic strains is very lengthy, because it takes many backcrosses to obtain an isogenic or homogeneous background. … agitar alterar violentamente crucigrama

The genetic etiology of critical congenital heart disease

Backcrossing - an overview ScienceDirect Topics

Backcrossing may be deliberately employed in animals to transfer a desirable trait in an animal of inferior genetic background to an animal of preferable genetic background. In gene-knockout experiments in particular, where the knockout is performed on easily cultured stem cell lines, but is required in an animal with a different genetic background, the knockout animal is backcrossed against the animal of the required genetic background. As the figure shows, each time that the … WebConsomic (chromosome substitution) strains (CSs) represent the most recent addition to the mouse genetic resources aimed to genetically analyze complex … nec rl39 リモコンWebNov 24, 2024 · Here, we utilized the A/J-11SM consomic strain and a set of chromosome 11 (Chr. 11) congenic strains developed from A/J-11SM to identify a candidate STZ-induced diabetes susceptibility gene. nec realtekオーディオドライバー

"WebCongenic (and consomic) strains contain a discrete DNA region derived from another strain (for consomic strains, this region is an entire chromosome; Table 31.1). Historically, congenic mice were developed by the repeated backcrossing of strain-specific alleles onto another strain background with the selection of the desired allele/region at ... " - Consomic strain

Consomic strain

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WebThe SMSR is a resource of special strains of mice that are important tools for genetic analysis of such complex diseases. They include panels of recombinant inbred (RI) and … http://www.findmice.org/summary?gaccid=MGI:3843498&states=archived&states=embryo&states=live&states=ovaries&states=sperm

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WebPubMed Central (PMC) WebIt is relatively easy to generate inbred congenic (nearly identical) and consomic strains. A consomic strain is an inbred strain with one of its chromosomes replaced by the homologous chromosome of another inbred strain via a series of marker-assisted backcrosses. Rat, rattus norvegicus, model, systems, organisms, homology.

WebNov 1, 2015 · This creates the consomic strain that shares with its host strain the same 1) genetic background (including chrY PAR, autosomes, chrX, mitochondrial DNA) and 2) pre- and postnatal maternal environment (including inoculated microbiota). WebFeb 11, 2016 · Of the 23 genes within the narrowed congenic interval, 12 were differentially expressed between the resistance vasculature of the 2 …

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WebApr 8, 2015 · The consomic strains have been derived from C57BL/6J (host strain) and A/J (donor strain) inbred lines. The work contributes to the value of the mouse as an animal model for studying the genetic background of differences in baseline circulating total and HDL cholesterol levels. The consomic strain survey suggested that mouse …

WebConsomic inbred strains are also created through successive backcrossing to a different inbred strain, but the choice of breeders is based on an entire chromosome, not just one … nec sde マニュアルWebGenetic background affects susceptibility to pancreatic ductal adenocarcinoma in the Ela-KRASG12D mouse model. In this model, KRAS oncogene expression is driven by an elastase promoter in acinar cells of the pancreas on an FVB/NTac (FVB) background agitar alterar violentamenteWebNov 1, 2010 · called a consomic strain in which part or an entire chromosome is moved from one inbred. strain to another. An example is the C57BL/6J-Chr11.3 PWD/Ph /ForeJ created by Dr. Jiri. agita precioWebany consomic strain within 6 months, by an F2 intercross of the consomic with the background parental strain. These rats are likely to become a national resource for rat research. The website, which currently gets 2,000 visits per month (figure 3), enables investigators to download data or to use the analytical agita powderWebNov 24, 2008 · Consomic strains have recently attracted attention as an advantageous method to screen for genes related to developmental, physiological, and behavioral phenotypes. Recently, a new set of consomic strains was established from the Japanese wild-derived mouse strain MSM/Ms and C57BL/6JJcl. By analyzing the entire consomic … agitare ingleseWebConsomic strains, in which one chromosome is derived from a donor strain and the other chromosomes are derived from the recipient strain, provide a powerful tool for the … agitare andre maggiWebNov 24, 2024 · These strains allow reproducible and efficient whole-chromosome mapping (Flint and Eskin, 2012 ). In contrast, consomic strains, also termed chromosome substitution strains, possess a substitution of one whole chromosome pair from the donor strain into the genetic background of the host strain. nec rl52 互換リモコン