WebJul 11, 2024 · CircRNAs are a subgroup of RNAs which form a circular molecule. During the splicing process the 3’ splice donor loops back to form a covalent bond with an upstream 5’ splice acceptor instead of the downstream 5’ acceptor. The majority of circRNAs are non-coding splice isoforms of protein coding genes showing tissue and time specific … WebApr 7, 2024 · A growing body of evidence shows that circular RNAs (circRNAs) participate in tumor growth and metastasis and also play crucial roles in the treatment and prognosis of various cancers. In this article, we identified a novel circRNA, circSOBP (has_circ_0001633), based on the results of high-throughput RNA sequencing, and its …
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WebMay 25, 2024 · Circular RNA (circRNA) is a new type of noncoding RNA that can form closed continuous loop structures with covalently joined 3′- and 5′-ends, which is in … WebMay 15, 2024 · Circular RNAs (circRNAs), which act as initiators and promoters of various diseases, were thought to be mostly noncoding RNAs (ncRNAs) in eukaryotes, until recent studies confirmed that some circRNAs have the function of encoding proteins. Accumulating research findings have proved that dysregulation of circRNAs is associated with the … high protein levels in blood test results
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WebToxicology and Cancer Biology Faculty Publications Toxicology and Cancer Biology 1-23-2024 Circular RNA circNOL10 Inhibits Lung Cancer Development by Promoting SCLM1-Mediated Transcriptional Regulation of the ... and circular RNAs (circRNAs), which represent a new type of noncoding RNAs, have become a recent topic of research. ... WebMay 25, 2024 · Cyclosporin A (CsA) is a well-known and effective drug that is commonly used in autoimmune diseases and allotransplantation. However, kidney toxicity and cardiotoxicity limit its use. Circular RNAs (circRNAs) play a crucial role in disease, especially cardiovascular disease. WebApr 8, 2024 · In the fight against glioblastoma, circular RNA is emerging as a functional molecule. However, how circular RNA (circRNA) is regulated and what role it plays is still a mystery. In this research, different bioinformatics approaches were used to evaluate glioblastoma circRNA sequencing and array data, with the goal of developing a putative … high protein levels in blood- cause