WebFeb 1, 2003 · biogenic polyamines, using the available. techniques to study interacting systems (summarized in Table 3). Up to now, the studies aimed to de-scribe details of … Polyamines promote homologous recombination (HR)-mediated double-strand break (DSB) repair. Polyamines enhance the DNA strand exchange activity of RAD51 recombinase. Depletion of polyamines sensitizes cells to genotoxic substances such as ionizing radiation and ultraviolet radiation. See more A polyamine is an organic compound having more than two amino groups. Alkyl polyamines occur naturally, but some are synthetic. Alkylpolyamines are colorless, hygroscopic, and water soluble. Near neutral pH, they … See more Ethyleneamines are a commercially-important class of synthetic polyamines with ethylene (-CH2CH2- linkages); global production capacity was estimated at 385,000 tonnes in … See more Spermidine is synthesized from putrescine, using an aminopropyl group from decarboxylated S-adenosyl-L-methionine (SAM). The reaction is catalyzed by spermidine synthase See more • Polyamines in cell cycle proliferation and cell death • Ornithine Decarboxylase: Expression and regulation in rat brain and in transgenic mice, 2002, Pekka Kilpelainen, Department of Biochemistry, University of Oulu. Extensive review of literature through 2001 on polyamine structure, properties, metabolism in mammals, and physiological and pathophysiological roles (See article Table of Contents) See more Low-molecular-weight linear polyamines are found in all forms of life. The principal examples are the triamine spermidine and the tetraamine See more Although it is known that the biosynthesis of polyamines is highly regulated, the biological function of polyamines is only partly understood. In their cationic ammonium form, they bind to DNA, and, in structure, they represent compounds with cations that are … See more The critical role of polyamines in cell growth has led to the development of a number of agents that interfere with polyamine metabolism. These agents are used in cancer … See more
Some factors influencing biogenic amines and polyamines
WebNov 7, 2024 · The biogenic amine intoxication leads to toxicological risks and health hazards that trigger psychoactive, vasoactive, and hypertensive effects resulting from consumption of high amounts of biogenic amines in foods. ... Ramirez FJ, Sanchez-Jimenez F. Biogenic amines and polyamines: Similar biochemistry for different … WebThey are important metabolic regulatory substances that participate in a variety of physiological and pathological processes, such as promoting cell differentiation, proliferation, and growth, and regulating nucleic acid and protein synthesis. 6 In the metabolic pathway of biogenic polyamines, ornithine is converted to putrescine by ornithine ... inclusion criteria example
(PDF) Selective Sensing of aliphatic biogenic polyamines by a ...
WebThe MOF is shown to serve as an efficient sensory material for detection of hazardous biogenic polyamines by ‘turn-off’ fluorescence quenching with rates (k q s) beyond the … WebPolyamines MeSH Descriptor Data 2024. Details; Qualifiers; MeSH Tree Structures; Concepts; MeSH Heading Polyamines Tree Number(s) D02.092.782 Unique ID ... Biogenic Amines [D02.092.211] Butylamines [D02.092.264] Catecholamines [D02.092.311] Chloramines [D02.092.348] Cyclohexylamines [D02.092.384] Web(1) Background: Spermidine is a biogenic polyamine that plays a crucial role in mammalian metabolism. As spermidine levels decline with age, spermidine supplementation is suggested to prevent or delay age-related diseases. However, valid pharmacokinetic data regarding spermidine remains lacking. Therefore, for the first time, the present study … inclusion criteria for bamlanivimab